Components of Bovine Colostrum
Bovine colostrum contains the perfect, complete and necessary nutritional factors for human. Not only that, but bovine colostrum also proven effective as one of the most important nutrition supplements to strengthen the immune system naturally, this magical ability is due to the optimal composition of bovine colostrum
Table comparing between the nutritional components in bovine colostrum and human colostrum
Bovine colostrum provides large amounts of energy and nutrients like protein, carbohydrate, oligosaccharides, amino acids, Vitamins, and Minerals. The sufficient and essential vitamins and minerals in the bovine colostrum enhance and protect comprehensively our health, including the new babies.
Vitamins: included are Vitamin A, Vitamin C, Vitamin D, Vitamin E, Thiamin (Vitamin B1), Riboflavin (Vitamin B2), Nicotinamide (Vitamin B3), Pantothenic acid (Vitamin B5), Pyrodoxin (Vitamin B6), folic acid (Vitamin B9), Cobalamin (vitamin B12) ...
Minerals & Inos: included Folic Acid, Calcium (Ca), Iron (Fe), magnesium (Mg), Manganese (Mn), Phosphorous (P), Potassium (K), Selenium (Se), Sodium (Na), Zinc (Zn ) ….
Carbohydrates: from simple sugars to complex oligosaccharides, carbohydrates are an important energy source and used in cellular recognition.
Amino Acids: consist of a large number of compounds that are the building blocks of proteins through the linking of peptide bonds. Amino acids are important for nutrition and muscle development.
Protein: Protein content in bovine colostrum 4 times higher than human colostrum while only half lactose. 500mg colostrum protein equivalent to the protein needed to offer more to the fetus in one day. colostral protein provides essential nutritional components for muscle and tissue development. Help to provide energy.
PRPs: Proline Rich Polypeptides (PRPs): small chains of amino acids that have a powerful effect in initiating and balancing immune responses. Functions include modulating the immune system, acting as molecular signaling devices, promoting growth and the differentiation of B-cells, stimulating Natural Kill cell (NK cell) activity and promoting the proliferation of leukocytes (white blood cells).
Fatty acids: Both Omega-3 & Omega-6 fatty acids are important components of cell membranes and they are the precursors to many other substances in the body such as those involved with regulating blood pressure and inflammatory responses. There is increasing support for omega-3 fatty acids in protecting against fatal heart disease and it is known that they have anti-inflammatory effects, which may be important in this and other diseases. There is also growing interest in the role of omega-3 fatty acids in the prevention of diabetes and certain types of cancer.
Lactalbumin: important nutrient and water-soluble protein found in milk which contains essential amino acids necessary for body growth and development.
Table comparing between the immune factors in bovine colostrum and human colostrum (Source: Stelwagen et al 2009)
With over 90 immune factors, bovine colostrum entirely likely help the body fight the immune-related illnesses: colds, diarrhea, ... The immune factors in bovine colostrum similar to those factors in the human body is almost absolute.
Lactoferrin: is one of the natural immune factors are important. Lactoferrin accounted for 6% of the total protein, has the ability to prevent the onset of diarrhea-causing virus, the virus that causes birth defects, virus infection otitis media and respiratory tract in children. Lactoferrin has the ability to penetrate the bacterial cell wall, allowing lysozyme go into bacterial cells to disrupt and destroy them.
Immunoglobulins (Ig): also known as antibodies, which are found in bovine colostrum (111 times) higher than the antibodies in human colostrum.
IgG are used by the immune system to identify, attack and neutralize foreign objects such as bacteria and viruses. IgG is like bodyguards protecting the body. IgG also helps to initiate a cascade of other immune functions.
IgA: strategically resides in areas like the gastrointestinal, respiratory and urogenital tracts to play a critical role in mucosal immunity by preventing specific pathogens from colonizing.
IgM: the first responder to pathogens entering the body, attacks bacteria and viruses, and rendering them inactive.
Cytokines: Interleukins, Interferon, tumor necrosis factor are a group of cytokines (secreted proteins and signal molecules) that were first seen to be expressed by white blood cells (leukocytes). The function of the immune system depends in a large part on interleukins.
Colostrum contains many of these biological response modifiers. These can be protein, peptide or glycoprotein signaling molecules that are used in cellular communications. Cytokines have a specific role as regulators of epithelial cell growth and development, including intestinal inflammation and epithelial restoration following mucosal damage. They are also important mediators in the regulation of immune and inflammatory responses.
Lactoperoxidase LPO: a major antibacterial enzyme found in colostrum. Protects the lactating mammary gland from infections. Partly activated by forming a complex with lysozyme. Also shown to work with lactoferrin for some antibacterial effects. Some viruses, like polioviruses, are sensitive to lactoperoxidase’s toxic effects to viruses.
Table comparing between the growth factors in bovine colostrum and human colostrum (Source: Playford et al , L. Elfstrand et al.)
The growth factors in bovine colostrum are constructed similar to the growth factors in human colostrum. Therefore the use of bovine colostrum is absolutely no detrimental to the health of human.
Epidermal Growth Factors (EGF): is a growth factor that stimulates cell growth, proliferation, and differentiation. The EGF family of growth factors can help modulate development of the epidermis, mammary gland, and gut.
Fibroblast Growth Factors (FGFs): are a family of growth factors, with members involved in angiogenesis, wound healing, embryonic development and various endocrine. FGFs are key players in the processes of proliferation and differentiation of wide variety of cells and tissues.
Insulin-like Growth Factor (IGF-1): the most abundant growth factors of bovine colostrum. These proteins are single chain polypeptides with amino acids. They play an important role in childhood growth and continues to have anabolic effects in adults
Platelet-derived Growth Factor (PDGF): one of numerous proteins that regulate cell growth and division, playing a significant role in blood vessel formation. Recombinant PDGF is used in medicine to help heal chronic ulcers and in orthopedic surgery and periodontistry to treat bone loss.
Transforming Growth Factors (TGF-alpha & TGF-beta): TGF-alpha induces epithelial tissue development. TGF-beta plays a crucial role in tissue regeneration, cell differentiation, formation of bone cartilage, and regulation of the immune system.
Growth hormone (GH): stimulates growth, cell reproduction, and cell regeneration in humans and other animals.
Vascular endothelial growth factor (VEGF): stimulates vasculogenesis and angiogenesis. It is part of the system that restores the oxygen supply to tissues when blood circulation